منابع مشابه
Scar-free healing
Mending wounds quickly while keeping them scar-free is not an impossible task. Mori et al. (page 43) find that shutting down a protein called osteopontin does the trick. Scars form when the inflammatory response that protects skin wounds against invading microbes induces the release of chemokines, which recruit fibroblasts. These cells then generate swathes of collagen to provide a new matrix f...
متن کاملScar-free healing: from embryonic mechanisms to adult therapeutic intervention.
In man and domestic animals, scarring in the skin after trauma, surgery, burn or sports injury is a major medical problem, often resulting in adverse aesthetics, loss of function, restriction of tissue movement and/or growth and adverse psychological effects. Current treatments are empirical, unreliable and unpredictable: there are no prescription drugs for the prevention or treatment of dermal...
متن کاملWound healing--scar wars.
Scafring following wounding is a major medical problem. In skin wounds or bums scarring often leads to adverse cosmesis and consequent psychological problems, adverse function particularly over joints and retardation of growth especially in children. Scarring in muscle adversely affects movement and can cause ankylosis. In abdominal and pelvic organs scarring can lead to life threatening strict...
متن کاملExpression of Integrin Α V Β 6 and Tgf - Β in Scar - Free Vs . Scar - Forming Wound Healing
Background: Raman spectroscopy is a non-invasive optical technique, which has the capability in determining the molecular structure and conformation of biochemical constitutes. Recently we developed a rapid real-time Raman spectrometer system, paving the way for clinical application of Raman spectroscopy. Hypothesis: The morphological structure and the bio-molecular constitutes have been altere...
متن کاملHuman Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth
Human mesenchymal stem cells (MSCs) are a promising candidate for cell-based transplantation and regenerative medicine therapies. Thus in the present study Wharton's Jelly Mesenchymal Stem Cells (WJ-MSCs) have been derived from extra embryonic umbilical cord matrix following removal of both arteries and vein. Also, to overcome the clinical limitations posed by fetal bovine serum (FBS) supplemen...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2008
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2051iti4